Signs of withdrawal from which type of substances may include psychomotor agitation and grand mal seizures?

The correct answer relates to the withdrawal from sedatives and anxiolytics, such as benzodiazepines and barbiturates. When individuals who have developed a dependency on these substances suddenly reduce or stop their intake, they can experience significant withdrawal symptoms. Psychomotor agitation is one of these symptoms, characterized by increased restlessness, anxiety, and an inability to sit still. Additionally, grand mal seizures can occur in severe cases of withdrawal from sedatives, highlighting the potential dangers of abrupt cessation after prolonged use.

In contrast, while opioids can lead to withdrawal symptoms like muscle aches and insomnia, they typically do not produce seizures as a withdrawal symptom. Stimulants can cause agitation and fatigue during withdrawal but are not associated with grand mal seizures. Hallucinogens, on the other hand, may cause perceptual disturbances but do not generally lead to severe physical withdrawal symptoms like seizures. Thus, the withdrawal symptoms associated specifically with sedatives and anxiolytics make this option the most accurate choice.